Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration

The terminal stages of neuronal degeneration and death in neurodegenerative diseases remain elusive. Autophagy is an essential catabolic process frequently failing in neurodegeneration. Selective autophagy routes have recently emerged, including nucleophagy, defined as degradation of nuclear compone...

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Pubblicato in:Curr Biol
Autori principali: Baron, Olga, Boudi, Adel, Dias, Catarina, Schilling, Michael, Nölle, Anna, Vizcay-Barrena, Gema, Rattray, Ivan, Jungbluth, Heinz, Scheper, Wiep, Fleck, Roland A., Bates, Gillian P., Fanto, Manolis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723708/
https://ncbi.nlm.nih.gov/pubmed/29174892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.10.054
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