Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration

The terminal stages of neuronal degeneration and death in neurodegenerative diseases remain elusive. Autophagy is an essential catabolic process frequently failing in neurodegeneration. Selective autophagy routes have recently emerged, including nucleophagy, defined as degradation of nuclear compone...

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Bibliografiset tiedot
Julkaisussa:Curr Biol
Päätekijät: Baron, Olga, Boudi, Adel, Dias, Catarina, Schilling, Michael, Nölle, Anna, Vizcay-Barrena, Gema, Rattray, Ivan, Jungbluth, Heinz, Scheper, Wiep, Fleck, Roland A., Bates, Gillian P., Fanto, Manolis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723708/
https://ncbi.nlm.nih.gov/pubmed/29174892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.10.054
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