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Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway
The Ras-Raf-MEK-ERK pathway plays a central role in tumorigenesis and is a target for anticancer therapy. The successful strategy based on the activation of cell death in Ras-expressing cells is associated with the suppression of kinases involved in Ras pathway. However, activation of cytoprotective...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723691/ https://ncbi.nlm.nih.gov/pubmed/29140794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101325 |
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