Adenosine A(2A) Receptor Deletion Blocks the Beneficial Effects of Lactobacillus reuteri in Regulatory T-Deficient Scurfy Mice

The lack of a functional Foxp3 transcription factor and regulatory T (Treg) cells causes lethal, CD4(+) T cell-driven autoimmune diseases in scurfy (SF) mice and humans. Recent studies have shown that adenosine A(2A) receptor activation limits inflammation and tissue damage, thereby playing an anti-...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: He, Baokun, Hoang, Thomas K., Tran, Dat Q., Rhoads, Jon Marc, Liu, Yuying
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723640/
https://ncbi.nlm.nih.gov/pubmed/29270168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01680
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