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Adenosine A(2A) Receptor Deletion Blocks the Beneficial Effects of Lactobacillus reuteri in Regulatory T-Deficient Scurfy Mice
The lack of a functional Foxp3 transcription factor and regulatory T (Treg) cells causes lethal, CD4(+) T cell-driven autoimmune diseases in scurfy (SF) mice and humans. Recent studies have shown that adenosine A(2A) receptor activation limits inflammation and tissue damage, thereby playing an anti-...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723640/ https://ncbi.nlm.nih.gov/pubmed/29270168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01680 |
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