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Decreased non-specific Adhesivity, Receptor Targeted (DART) nanoparticles exhibit improved dispersion, cellular uptake, and tumor retention in invasive gliomas

The most common and deadly form of primary brain cancer, glioblastoma (GBM), is characterized by significant intratumoral heterogeneity, microvascular proliferation, immune system suppression, and brain tissue invasion. Delivering effective and sustained treatments to the invasive GBM cells intermix...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Wadajkar, Aniket S., Dancy, Jimena G., Roberts, Nathan B., Connolly, Nina P., Strickland, Dudley K., Winkles, Jeffrey A., Woodworth, Graeme F., Kim, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723214/
https://ncbi.nlm.nih.gov/pubmed/28887134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.09.006
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