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Non-specific binding and steric hindrance thresholds for penetration of particulate drug carriers within tumor tissue
Therapeutic nanoparticles (NPs) approved for clinical use in solid tumor therapy provide only modest improvements in patient survival, in part due to physiological barriers that limit delivery of the particles throughout the entire tumor. Here, we explore the thresholds for NP size and surface poly(...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499233/ https://ncbi.nlm.nih.gov/pubmed/27460683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.07.034 |
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