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Transcription within Condensed Chromatin: Steric Hindrance Facilitates Elongation
During eukaryotic transcription, RNA-polymerase activity generates torsional stress in DNA, having a negative impact on the elongation process. Using our previous studies of chromatin fiber structure and conformational transitions, we suggest that this torsional stress can be alleviated, thanks to a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830436/ https://ncbi.nlm.nih.gov/pubmed/20197036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.054 |
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