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Transcription within Condensed Chromatin: Steric Hindrance Facilitates Elongation

During eukaryotic transcription, RNA-polymerase activity generates torsional stress in DNA, having a negative impact on the elongation process. Using our previous studies of chromatin fiber structure and conformational transitions, we suggest that this torsional stress can be alleviated, thanks to a...

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Bibliografske podrobnosti
Main Authors: Bécavin, Christophe, Barbi, Maria, Victor, Jean-Marc, Lesne, Annick
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830436/
https://ncbi.nlm.nih.gov/pubmed/20197036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.054
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