Lataa...

Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β

Monoclonal antibodies (mAbs) have not been used as positron emission tomography (PET) ligands for in vivo imaging of the brain because of their limited passage across the blood-brain barrier (BBB). However, due to their high affinity and specificity, mAbs may be an attractive option for brain PET if...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Sehlin, Dag, Fang, Xiaotian T., Meier, Silvio R., Jansson, Malin, Syvänen, Stina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722892/
https://ncbi.nlm.nih.gov/pubmed/29222502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17358-2
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!