A Combined In Vivo HSC Transduction/Selection Approach Results in Efficient and Stable Gene Expression in Peripheral Blood Cells in Mice

We recently reported on an in vivo hematopoietic stem cell (HSC) gene therapy approach. It involves the subcutaneous injections of G-CSF/AMD3100 to mobilize HSCs from the bone marrow into the peripheral blood stream and the intravenous injection of an integrating helper-dependent adenovirus vector s...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Wang, Hongjie, Richter, Maximilian, Psatha, Nikoletta, Li, Chang, Kim, Jiho, Liu, Jing, Ehrhardt, Anja, Nilsson, Susan K., Cao, Benjamin, Palmer, Donna, Ng, Philip, Izsvák, Zsuzsanna, Haworth, Kevin G., Kiem, Hans-Peter, Papayannopoulou, Thalia, Lieber, André
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722719/
https://ncbi.nlm.nih.gov/pubmed/29255741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.11.004
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