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Small molecule delivery to solid tumors with chitosan-coated PLGA particles: A lesson learned from comparative imaging

For polymeric nanoparticles (NPs) to deliver more drugs to tumors than free drug solution, it is critical that the NPs establish interactions with tumor cells and avoid removal from the tumors. Since traditional polyethylene glycol (PEG) surface layer interferes with the cell-NP interaction in tumor...

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Bibliographische Detailangaben
Veröffentlicht in:J Control Release
Hauptverfasser: Park, Jinho, Pei, Yihua, Hyun, Hyesun, Castanares, Mark A., Collins, David S., Yeo, Yoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722701/
https://ncbi.nlm.nih.gov/pubmed/29111150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.10.037
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