A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size

The Hippo/Yki and RB/E2F pathways both regulate tissue growth by affecting cell proliferation and survival, but interactions between these parallel control systems are poorly defined. In this study, we demonstrate that interaction between Drosophila E2F1 and Sd disrupts Yki/Sd complex formation and...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Zhang, Peng, Pei, Chunli, Wang, Xi, Xiang, Jinyi, Sun, Bao-Fa, Cheng, Yongsheng, Qi, Xiaolong, Marchetti, Marco, Xu, Jia-Wei, Sun, Ying-Pu, Edgar, Bruce A., Yuan, Zengqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722641/
https://ncbi.nlm.nih.gov/pubmed/29207260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.10.033
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