Identifying tumor promoting genomic alterations in tumor-associated fibroblasts via retrovirus-insertional mutagenesis

Tumor-associated fibroblasts (TAFs) are often essential for solid tumor growth. However, few genetic or epigenetic alterations have been found in TAFs during the progression of solid tumors. Employing a tumor-stromal cell co-injection model, we adapted here retroviral-insertional mutagenesis to stro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rong, Lijie, Bian, Yangyang, Liu, Shubai, Liu, Xiaoman, Li, Xiao, Liu, Haiyang, Zhou, Jinxue, Peng, Jirun, Zhang, Henghui, Chen, Hongsong, Qin, Zhihai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722558/
https://ncbi.nlm.nih.gov/pubmed/29228606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21881
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