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Synthesis of cananodine by intramolecular epoxide opening

Cananodine is a guaipyridine alkaloid with activity against liver cancer. Cananodine was synthesized using a remarkable intramolecular opening of a trisubstituted epoxide as the key step in construction of the seven-membered carbocycle of the target. The epoxide opening strategy allows all four ster...

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Bibliografiske detaljer
Udgivet i:Tetrahedron Lett
Main Authors: Shelton, Patrick, Ligon, Toby J., Dell (née Meyer), Jennifer M., Yarbrough, Loagan, Vyvyan, James R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722248/
https://ncbi.nlm.nih.gov/pubmed/29230072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2017.07.080
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