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Inhibition of Vascular c‐Jun N‐Terminal Kinase 2 Improves Obesity‐Induced Endothelial Dysfunction After Roux‐en‐Y Gastric Bypass
BACKGROUND: Roux‐en‐Y gastric bypass (RYGB) reduces obesity‐associated comorbidities and cardiovascular mortality. RYGB improves endothelial dysfunction, reducing c‐Jun N‐terminal kinase (JNK) vascular phosphorylation. JNK activation links obesity with insulin resistance and endothelial dysfunction....
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Veröffentlicht in: | J Am Heart Assoc |
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Hauptverfasser: | , , , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
John Wiley and Sons Inc.
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5721746/ https://ncbi.nlm.nih.gov/pubmed/29138180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006441 |
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