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Glycoprotein Ib clustering in platelets can be inhibited by α-linolenic acid as revealed by cryo-electron tomography

Platelet adhesion to the sub-endothelial matrix and damaged endothelium occurs through a multi-step process mediated in the initial phase by glycoprotein Ib binding to von Willebrand factor (vWF), which leads to the subsequent formation of a platelet plug. The plant-derived ω-3 fatty acid α-linoleni...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Stivala, Simona, Sorrentino, Simona, Gobbato, Sara, Bonetti, Nicole R., Camici, Giovanni G., Lüscher, Thomas F., Medalia, Ohad, Beer, Jürg H.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271563/
https://ncbi.nlm.nih.gov/pubmed/31439672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.220988
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