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Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells

Recent evidence indicates that hematopoietic stem and progenitor cells (HSPCs) can serve as vehicles for therapeutic molecular delivery to the brain by contributing to the turnover of resident myeloid cell populations. However, such engraftment needs to be fast and efficient to exert its therapeutic...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Capotondo, Alessia, Milazzo, Rita, Garcia-Manteiga, Jose M., Cavalca, Eleonora, Montepeloso, Annita, Garrison, Brian S., Peviani, Marco, Rossi, Derrick J., Biffi, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721728/
https://ncbi.nlm.nih.gov/pubmed/29226242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1701211
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