Interferon‐alpha‐induced hepatitis C virus clearance restores p53 tumor suppressor more than direct‐acting antivirals

The mechanism why hepatitis C virus (HCV) clearance by direct‐acting antivirals (DAAs) does not eliminate the risk of hepatocellular carcinoma (HCC) among patients with advanced cirrhosis is unclear. Many viral and bacterial infections degrade p53 in favor of cell survival to adapt an endoplasmic re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hepatol Commun
Prif Awduron: Aydin, Yucel, Chatterjee, Animesh, Chandra, Partha K, Chava, Srinivas, Chen, Weina, Tandon, Anamika, Dash, Asha, Chedid, Milad, Moehlen, Martin W, Regenstein, Frederic, Balart, Luis A, Cohen, Ari, Lu, Hua, Wu, Tong, Dash, Srikanta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721446/
https://ncbi.nlm.nih.gov/pubmed/29404458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1025
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