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Selective HDAC6 inhibition decreases early stage of lupus nephritis by down‐regulating both innate and adaptive immune responses

We have demonstrated previously that histone deacetylase (HDAC6) expression is increased in animal models of systemic lupus erythematosus (SLE) and that inhibition of HDAC6 decreased disease. In our current studies, we tested if an orally active selective HDAC6 inhibitor would decrease disease patho...

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Vydáno v:Clin Exp Immunol
Hlavní autoři: Ren, J., Liao, X., Vieson, M. D., Chen, M., Scott, R., Kazmierczak, J., Luo, X. M., Reilly, C. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721231/
https://ncbi.nlm.nih.gov/pubmed/28876451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13046
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