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HDAC Expression and Activity is Upregulated in Diseased Lupus-prone Mice
Prior studies have shown that pan-HDAC inhibition can decrease disease in lupus mice; however, the mechanisms(s) remain to be elucidated. MRL/MpJ-Fas(lpr) (MRL/lpr) mice develop a lupus-like disease characterized by anti-dsDNA production, lymphoproliferation, and immune complex-mediated glomerulonep...
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| Publicado no: | Int Immunopharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666739/ https://ncbi.nlm.nih.gov/pubmed/26471208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2015.10.006 |
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