Rapid DNA replication origin licensing protects stem cell pluripotency

Complete and robust human genome duplication requires loading minichromosome maintenance (MCM) helicase complexes at many DNA replication origins, an essential process termed origin licensing. Licensing is restricted to G1 phase of the cell cycle, but G1 length varies widely among cell types. Using...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Matson, Jacob Peter, Dumitru, Raluca, Coryell, Philip, Baxley, Ryan M, Chen, Weili, Twaroski, Kirk, Webber, Beau R, Tolar, Jakub, Bielinsky, Anja-Katrin, Purvis, Jeremy E, Cook, Jeanette Gowen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Chromosomes and Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720591/
https://ncbi.nlm.nih.gov/pubmed/29148972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30473
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