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The TRPM2 ion channel is required for sensitivity to warmth

How do we detect warmth? Thermally-activated ion channels expressed in somatosensory neurons detect the entire thermal range from extreme heat (TRPV2), painful heat (TRPV1, TRPM3, ANO1), non-painful warmth (TRPV3 and TRPV4) and non-painful coolness (TRPM8) through to painful cold (TRPA1)1–7. Genetic...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nature
Main Authors: Tan, Chun-Hsiang, McNaughton, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720344/
https://ncbi.nlm.nih.gov/pubmed/27533035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19074
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