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TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide
Neutrophils must navigate accurately towards pathogens in order to destroy invaders and thus defend our bodies against infection. Here we show that hydrogen peroxide, a potent neutrophil chemoattractant, guides chemotaxis by activating calcium-permeable TRPM2 ion channels and generating an intracell...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085234/ https://ncbi.nlm.nih.gov/pubmed/33927223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88224-5 |
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