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Sex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite)
Metapristone is the primary metabolite of the abortifacient mifepristone (RU486), and is being developed as a safe and effective cancer metastatic chemopreventive agent for both sexes. Here, we systematically investigated the sex-related pharmacokinetics of metapristone in both rats and dogs, and ex...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719405/ https://ncbi.nlm.nih.gov/pubmed/29215040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17225-0 |
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