Synthesis, Spectral Characterization, and In Vitro Cellular Activities of Metapristone, a Potential Cancer Metastatic Chemopreventive Agent Derived from Mifepristone (RU486)

Mifepristone (RU486) is marketed and used widely by women as an abortifacient, and experimentally for psychotic depression and anticancer treatments. After administration, metapristone is found to be the most predominant metabolite of mifepristone. We hypothesized that adhesion of circulating tumor...

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Detalhes bibliográficos
Main Authors: Wang, Jichuang, Chen, Jianzhong, Wan, Liyuan, Shao, Jingwei, Lu, Yusheng, Zhu, Yewei, Ou, Minrui, Yu, Suhong, Chen, Haijun, Jia, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933578/
https://ncbi.nlm.nih.gov/pubmed/24442753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9559-2
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