Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4

Dengue vaccine trials have revealed deficits in our understanding of the mechanisms of protective immunity, demonstrating a need to measure epitope-specific antibody responses against each DENV serotype. HmAb 5J7 binds to a complex, 3-monomer spanning quaternary epitope in the DENV3 envelope (E) pro...

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書誌詳細
出版年:Sci Rep
主要な著者: Widman, Douglas G., Young, Ellen, Nivarthi, Usha, Swanstrom, Jesica A., Royal, Scott R., Yount, Boyd L., Debbink, Kari, Begley, Matthew, Marcet, Stephanie, Durbin, Anna, de Silva, Aravinda M., Messer, William B., Baric, Ralph S.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719398/
https://ncbi.nlm.nih.gov/pubmed/29215033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17355-5
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