High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study

Pancreatic cancer is among the most lethal cancers with poorly tolerated treatments. There is increasing interest in using high-dose intravenous ascorbate (IVC) in treating this disease partially because of its low toxicity. IVC bypasses bioavailability barriers of oral ingestion, provides pharmacol...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Polireddy, Kishore, Dong, Ruochen, Reed, Gregory, Yu, Jun, Chen, Ping, Williamson, Stephen, Violet, Pierre-Christian, Pessetto, Ziyan, Godwin, Andrew K., Fan, Fang, Levine, Mark, Drisko, Jeanne A., Chen, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719364/
https://ncbi.nlm.nih.gov/pubmed/29215048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17568-8
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