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Structural analysis of the complex between influenza B nucleoprotein and human importin-α

Influenza viruses are negative strand RNA viruses that replicate in the nucleus of the cell. The viral nucleoprotein (NP) is the major component of the viral ribonucleoprotein. In this paper we show that the NP of influenza B has a long N-terminal tail of 70 residues with intrinsic flexibility. This...

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Publicat a:Sci Rep
Autors principals: Labaronne, Alice, Milles, Sigrid, Donchet, Amélie, Jensen, Malene Ringkjøbing, Blackledge, Martin, Bourhis, Jean-Marie, Ruigrok, Rob W. H., Crépin, Thibaut
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719345/
https://ncbi.nlm.nih.gov/pubmed/29215074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17458-z
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