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Structural analysis of the complex between influenza B nucleoprotein and human importin-α

Influenza viruses are negative strand RNA viruses that replicate in the nucleus of the cell. The viral nucleoprotein (NP) is the major component of the viral ribonucleoprotein. In this paper we show that the NP of influenza B has a long N-terminal tail of 70 residues with intrinsic flexibility. This...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Labaronne, Alice, Milles, Sigrid, Donchet, Amélie, Jensen, Malene Ringkjøbing, Blackledge, Martin, Bourhis, Jean-Marie, Ruigrok, Rob W. H., Crépin, Thibaut
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719345/
https://ncbi.nlm.nih.gov/pubmed/29215074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17458-z
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