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Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry

Sessile serrated adenomas are the precursor polyp of approximately 20% of colorectal carcinomas. Sessile serrated adenomas with dysplasia are rarely encountered and represent an intermediate step to malignant progression, frequently associated with loss of MLH1 expression. Accurate diagnosis of thes...

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Pubblicato in:Mod Pathol
Autori principali: Liu, Cheng, Walker, Neal I, Leggett, Barbara A, Whitehall, Vicki LJ, Bettington, Mark L, Rosty, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719122/
https://ncbi.nlm.nih.gov/pubmed/28752838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2017.92
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