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Nitric oxide mediates apoptosis and mitochondrial dysfunction and plays a role in growth hormone deficiency by nivalenol in GH3 cells

Nivalenol (NIV), a type B trichothecenes commonly found in cereal crops, can cause growth impairment in animals. However, limited information about its mechanisms is available. Trichothecenes have been characterized as an inhibitor of protein synthesis and induce apoptosis in cells. Oxidative stress...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Deyu, Cui, Luqing, Guo, Pu, Xue, Xijuan, Wu, Qinghua, Hussain, Hafiz Iftikhar, Wang, Xu, Yuan, Zonghui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719085/
https://ncbi.nlm.nih.gov/pubmed/29213091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16908-y
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