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Nitric oxide mediates apoptosis and mitochondrial dysfunction and plays a role in growth hormone deficiency by nivalenol in GH3 cells

Nivalenol (NIV), a type B trichothecenes commonly found in cereal crops, can cause growth impairment in animals. However, limited information about its mechanisms is available. Trichothecenes have been characterized as an inhibitor of protein synthesis and induce apoptosis in cells. Oxidative stress...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Huang, Deyu, Cui, Luqing, Guo, Pu, Xue, Xijuan, Wu, Qinghua, Hussain, Hafiz Iftikhar, Wang, Xu, Yuan, Zonghui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719085/
https://ncbi.nlm.nih.gov/pubmed/29213091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16908-y
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