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Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism
Neointimal hyperplasia is a product of VSMC replication and consequent accumulation within the blood vessel wall. In this study, we determined whether inhibition of protein kinase CK2 and the resultant stabilisation of proline-rich homeodomain (PRH) could suppress VSMC proliferation. Both silencing...
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Publicado no: | Vascul Pharmacol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5718878/ https://ncbi.nlm.nih.gov/pubmed/28927755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2017.09.004 |
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