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CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding

The proline-rich homeodomain protein (PRH/Hex) regulates transcription by binding to specific DNA sequences and regulates mRNA transport by binding to translation initiation factor eIF4E. Protein kinase CK2 plays multiple roles in the regulation of gene expression and cell proliferation. Here, we sh...

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Bibliografiske detaljer
Main Authors: Soufi, Abdenour, Noy, Peter, Buckle, Malcolm, Sawasdichai, Anyaporn, Gaston, Kevin, Jayaraman, Padma-Sheela
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691835/
https://ncbi.nlm.nih.gov/pubmed/19324893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp197
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