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Persistence of DNA adducts, hypermutation and acquisition of cellular resistance to alkylating agents in glioblastoma
Glioblastoma is a lethal form of brain tumour usually treated by surgical resection followed by radiotherapy and an alkylating chemotherapeutic agent. Key to the success of this multimodal approach is maintaining apoptotic sensitivity of tumour cells to the alkylating agent. This initial treatment l...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5718815/ https://ncbi.nlm.nih.gov/pubmed/29020502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1385680 |
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