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Gut Microbiome Interactions with Drug Metabolism, Efficacy and Toxicity

The gut microbiota have both direct and indirect effects on drug and xenobiotic metabolism and this can have consequences for both efficacy and toxicity. Indeed microbiome-driven drug metabolism is essential for the activation of certain prodrugs such as e.g., azo drugs such as prontosil and neopron...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Wilson, Ian D, Nicholson, Jeremy K
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718288/
https://ncbi.nlm.nih.gov/pubmed/27591027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2016.08.002
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