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Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
We provide a demonstration in humans of the principle of pharmacometabonomics by showing a clear connection between an individual's metabolic phenotype, in the form of a predose urinary metabolite profile, and the metabolic fate of a standard dose of the widely used analgesic acetaminophen. Pre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731842/ https://ncbi.nlm.nih.gov/pubmed/19667173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904489106 |
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