ABIN1 Determines Severity of Glomerulonephritis via Activation of Intrinsic Glomerular Inflammation

Transcription factor NF-κB regulates expression of numerous genes that control inflammation and is activated in glomerular cells in glomerulonephritis (GN). We previously identified genetic variants for a NF-κB regulatory, ubiquitin-binding protein ABIN1 as risk factors for GN in systemic autoimmuni...

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Udgivet i:Am J Pathol
Main Authors: Korte, Erik A., Caster, Dawn J., Barati, Michelle T., Tan, Min, Zheng, Shirong, Berthier, Celine C., Brosius, Frank C., Vieyra, Mark B., Sheehan, Ryan M., Kosiewicz, Michele, Wysoczynski, Marcin, Gaffney, Patrick M., Salant, David J., McLeish, Kenneth R., Powell, David W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718094/
https://ncbi.nlm.nih.gov/pubmed/28935578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.018
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