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ABIN1 Determines Severity of Glomerulonephritis via Activation of Intrinsic Glomerular Inflammation
Transcription factor NF-κB regulates expression of numerous genes that control inflammation and is activated in glomerular cells in glomerulonephritis (GN). We previously identified genetic variants for a NF-κB regulatory, ubiquitin-binding protein ABIN1 as risk factors for GN in systemic autoimmuni...
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| Veröffentlicht in: | Am J Pathol |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5718094/ https://ncbi.nlm.nih.gov/pubmed/28935578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.018 |
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