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Decreased expression of the β(2) integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

BACKGROUND: Lymphocyte Function-Associated Antigen-1 (LFA-1; CD18/CD11a) is one of the main adhesion molecules used by immune cells to infiltrate the liver under inflammatory conditions. Recently, the expression of this integrin has also been reported on several solid tumors, including colorectal ca...

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Pubblicato in:BMC Cancer
Autori principali: Benedicto, Aitor, Marquez, Joana, Herrero, Alba, Olaso, Elvira, Kolaczkowska, Elzbieta, Arteta, Beatriz
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718006/
https://ncbi.nlm.nih.gov/pubmed/29207960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3823-2
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