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TDP2, TOP2, and SUMO: what is ZATT about?

Recently, ZATT (also known as ZNF451 or Zpf451) was reported by Schellenberg et al. to aid the removal of Topoisomerase II cleavage complexes by stimulating the phosphodiesterase activity of Tyrosyl DNA Phosphodiesterase 2. Although the full implication of this discovery is unknown, it will help us...

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Detalles Bibliográficos
Publicado en:Cell Res
Main Authors: Zagnoli-Vieira, Guido, Caldecott, Keith W
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717409/
https://ncbi.nlm.nih.gov/pubmed/29160298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.147
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