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Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug?
Paclitaxel is a successful anti-cancer drug that kills cancer cells in two-dimensional culture through perturbation of mitosis, but whether it causes tumour regression by anti-mitotic actions is controversial. Drug candidates that specifically target mitosis, including inhibitors of kinesin-5, AurkA...
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| Publicado no: | Open Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5717346/ https://ncbi.nlm.nih.gov/pubmed/29142107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170182 |
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