Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation

Pericytes have been identified as a major source of myofibroblasts in renal interstitial fibrosis (RIF). The overactivation of several signaling pathways, mainly the TGF-β and PDGF pathways, initiates the pericyte-myofibroblast transition during RIF. Key receptors in these two pathways have been sho...

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Udgivet i:Sci Rep
Main Authors: Wang, Nan, Deng, Yiyao, Liu, Anqi, Shen, Nan, Wang, Weidong, Du, Xiangning, Tang, Qingzhu, Li, Shuangxin, Odeh, Zach, Wu, Taihua, Lin, Hongli
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717002/
https://ncbi.nlm.nih.gov/pubmed/29209018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17193-5
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