Targeting LncRNA HOTAIR suppresses cancer stemness and metastasis in oral carcinomas stem cells through modulation of EMT

Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate diverse cellular processes, such as cell growth, apoptosis and tumorigenesis. However, the functional roles of lncRNAs and mechanistic analysis of their interplays with oncogenic pathways in oral cancer remain largely unknown...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Lu, Ming-Yi, Liao, Yi-Wen, Chen, Pei-Yin, Hsieh, Pei-Ling, Fang, Chih-Yuan, Wu, Chia-Yu, Yen, Ming-Liang, Peng, Bou-Yue, Wang, Dayen Peter, Cheng, Hsin-Chung, Wu, Ching-Zong, Shih, Yung-Hsun, Wang, Duen-Jeng, Yu, Cheng-Chia, Tsai, Lo-Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716749/
https://ncbi.nlm.nih.gov/pubmed/29228709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21614
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