YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways

The Hippo pathway is an evolutionarily conserved signaling pathway that regulates proliferation and apoptosis to control organ size during developmental growth. Yes-associated protein 1 (YAP1), the terminal effector of the Hippo pathway, is a transcriptional co-activator and a potent growth promoter...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Andrade, Daniel, Mehta, Meghna, Griffith, James, Panneerselvam, Janani, Srivastava, Akhil, Kim, Tae-Dong, Janknecht, Ralf, Herman, Terence, Ramesh, Rajagopal, Munshi, Anupama
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716745/
https://ncbi.nlm.nih.gov/pubmed/29228705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21913
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