A systematic assessment of chemical, genetic, and epigenetic factors influencing the activity of anticancer drug KP1019 (FFC14A)

KP1019 ([trans-RuCl(4)(1H-indazole)(2)]; FFC14A) is one of the promising ruthenium-based anticancer drugs undergoing clinical trials. Despite the pre-clinical and clinical success of KP1019, the mode of action and various factors capable of modulating its effects are largely unknown. Here, we used t...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Golla, Upendarrao, Swagatika, Swati, Chauhan, Sakshi, Tomar, Raghuvir Singh
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716741/
https://ncbi.nlm.nih.gov/pubmed/29228701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21416
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