Overexpression of CAPN2 promotes cell metastasis and proliferation via AKT/mTOR signaling in renal cell carcinoma

The calpain 2 (CAPN2) is upregulated in various malignant carcinomas. Previous studies have reported that CAPN2 functioned as an oncogenic factor in human cancers. However, its clinical role and potential effects on cell metastasis and proliferation in renal cell carcinoma (RCC) remain unknown. In t...

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Vydáno v:Oncotarget
Hlavní autoři: Miao, Chenkui, Liang, Chao, Tian, Ye, Xu, Aiming, Zhu, Jundong, Zhao, Kai, Zhang, Jianzhong, Hua, Yibo, Liu, Shouyong, Dong, Huiyu, Zhang, Chao, Su, Shifeng, Li, Pu, Qin, Chao, Wang, Zengjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716693/
https://ncbi.nlm.nih.gov/pubmed/29228653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22083
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