Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway

The mRNA expression of CAPN2 was upregulated in CRPC cells (DU145 and PC3) than that in non-CRPC cells. Silencing CAPN2 expression could inhibit DU145 and PC3 cells proliferation by cell cycle arrest at G1 phase. Knockdown of CPAN2 level suppressed the migration and invasion capacity of CRPC cells b...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Li, Pu, Miao, Chenkui, Liang, Chao, Shao, Pengfei, Wang, Zengjun, Li, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322456/
https://ncbi.nlm.nih.gov/pubmed/28280729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2593674
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