Deletion of lynx1 reduces the function of α6* nicotinic receptors

The α6 nicotinic acetylcholine receptor (nAChR) subunit is an attractive drug target for treating nicotine addiction because it is present at limited sites in the brain including the reward pathway. Lynx1 modulates several nAChR subtypes; lynx1-nAChR interaction sites could possibly provide drug tar...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Parker, Rell L., O’Neill, Heidi C., Henley, Beverley M., Wageman, Charles R., Drenan, Ryan M., Marks, Michael J., Miwa, Julie M., Grady, Sharon R., Lester, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716591/
https://ncbi.nlm.nih.gov/pubmed/29206881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188715
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