Monodisperse measurement of the biotin-streptavidin interaction strength in a well-defined pulling geometry

The widely used interaction of the homotetramer streptavidin with the small molecule biotin has been intensively studied by force spectroscopy and has become a model system for receptor ligand interaction. However, streptavidin’s tetravalency results in diverse force propagation pathways through the...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Sedlak, Steffen M., Bauer, Magnus S., Kluger, Carleen, Schendel, Leonard C., Milles, Lukas F., Pippig, Diana A., Gaub, Hermann E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716544/
https://ncbi.nlm.nih.gov/pubmed/29206886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188722
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