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Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are responsible for the majority of excitatory transmission at the synaptic cleft. Mechanically speaking, agonist binding to the ligand binding domain (LBD) activates the receptor by triggering a conformational change that is...
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| Izdano u: | J Phys Chem B |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716343/ https://ncbi.nlm.nih.gov/pubmed/29065265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b06862 |
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