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Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are responsible for the majority of excitatory transmission at the synaptic cleft. Mechanically speaking, agonist binding to the ligand binding domain (LBD) activates the receptor by triggering a conformational change that is...
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| Publié dans: | J Phys Chem B |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716343/ https://ncbi.nlm.nih.gov/pubmed/29065265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b06862 |
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