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Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are responsible for the majority of excitatory transmission at the synaptic cleft. Mechanically speaking, agonist binding to the ligand binding domain (LBD) activates the receptor by triggering a conformational change that is...

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Dades bibliogràfiques
Publicat a:J Phys Chem B
Autors principals: Yu, Alvin, Lau, Albert Y.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716343/
https://ncbi.nlm.nih.gov/pubmed/29065265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b06862
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